Endocrine Abstracts

Thyroid diseases affect up to 4% of all pregnancies. Several evidence-based recommendations have been created to observe and treat thyroid diseases in pregnant women. We studied whether the diagnostics and treatment of hypothyroidism among pregnant women have improved in the course of time. Data consisted of all singleton pregnancies (N=571785) during 2004–2013 in Finland, collected from the Finnish Medical Birth Register (MBR). Data on maternal thyroid diseases ...

Introduction: Autoimmunity is an important etiological factor of premature ovarian insufficiency (POI, menopause <40 years). It has been estimated that 4-50 % of POI cases are of autoimmune origin. Only a few studies, with sample sizes of dozens to hundreds POI cases, have investigated the prevalence of autoimmune diseases in women with POI. We aimed to assess in an essentially larger data set the prevalence of severe autoimmune diseases treated in tertiary care prior to P...

Background: The risk of type 2 diabetes (T2D) in PCOS is associated with BMI, but prospective data regarding risk of T2D in PCOS are limited. We investigated prospective risk of T2D in Nordic women with PCOS compared to controls.Methods: National register-based study in women with PCOS and age-matched controls originating from Denmark (PCOS Denmark, (n=27,016, controls, (n=133,994), Finland (PCOS Finland, (n=20,467, controls, (...